Our research spans and merges three fields: drug delivery strategies, amyloid diseases, and cancer therapeutics. Our collaborations, both within the United Arab Emirates and worldwide, expand and contextualize our research for broader applications.
Our students are also actively involved in designing and conducting their own research within these fields in their capstone projects. Learn more by clicking on the links below.
Background: Artistic representation of research targets.
Meet our Team
Our team is a diverse group of post-docs, research assistants, instructors, and students. And one cactus.
Palanikumar, L., Al-Hosani, S., Kalmouni, M., Saleh, H. & Magzoub, M.* (2020) Hexokinase II-derived cell-penetrating peptide mediates delivery of microRNA mimic for cancer-selective cytotoxicity. Biochemistry, in press.
Palanikumar, L., Al-Hosani, S., Kalmouni, M., Nguyen, V.P., Ali, L., Pasricha, R., Barrera, F.N. & Magzoub, M.* (2020) pH-responsive high stability polymeric nanoparticles for targeted delivery of anticancer therapeutics. Commun. Biol. 3, 95.
Sharma, S.K.S., Al-Hosani, S., Kalmouni, M., Nair, A.R., Palanikumar, L., Pasricha, R., Sadler, K.C., Magzoub, M. & Jagannathan, R. (2020) Supercritical CO2 processing generates aqueous cisplatin with enhanced cancer specificity. ACS Omega 5, 4558−4567.
Henning-Knechtel, A., Kumar, S., Wallin, C., Król, S., Wärmländer, S., Jarvet, J., Esposito, G., Kirmizialtin, A., Gräslund, A., Hamilton, A.D. & Magzoub, M.* (2020) Designed cell-penetrating peptide inhibiters of amyloid-beta (Aβ) aggregation and cytotoxicity. Cell Rep. Phys. Sci. 1,100014.
Pansieri, J., Ostojić, L., Iashchishyn, I.A., Magzoub, M., Wallin, C., Wärmländer, S., Gräslund, A., Ngoc, M.N., Smirnovas, V., Svedruzic, Z. & Morozova-Roche, L.A. (2019) Pro-inflammatory S100A9 protein aggregation promoted by NCAM1 peptide constructs. ACS Chem. Biol. 14, 1410−1417.
Kalmouni, M., Al Hosani, S. & Magzoub, M.* (2019) Cancer Targeting Peptides. Cell Mol. Life Sci. 76, 2171-2183.
Nguyen, V.P., Palanikumar, L., Kennel, S.J., Ye, Y., Alves, D.S., Wall, J.S., Magzoub, M. & Barrera, F.N. (2019) Mechanistic insights into the pH-dependent membrane peptide ATRAM. J. Control. Release 298, 142-153.
Background: Small molecule inhibitors of amyloid-beta, designed and created by Khulood Alawadi, NYUAD.