Our Research
Our research spans and merges three fields: drug delivery strategies, amyloid diseases, and cancer therapeutics. Our collaborations, both within the United Arab Emirates and worldwide, expand and contextualize our research for broader applications.
Our students are also actively involved in designing and conducting their own research within these fields in their capstone projects. Learn more by clicking on the links below.
Background: Artistic representation of research targets.




Meet our Team
Our team is a diverse group of post-docs, research assistants, instructors, and students. And one cactus.



LATEST Publications
L. Palanikumar, Karpauskaite, L., Hassan, S., Alam, M., Al-Sayegh, M., Chehade, I., Maity, D., Ali, L., Falls, Z., Samudrala, R., Kalmouni, M., Hunashal, Y., Ahmed, J., Karapetyan, S., Pasricha, R., Esposito, G., Afzal, A.J., Hamilton, A.D.*, Kumar, S.* & Magzoub, M.* (2020) Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function. bioRxiv.
Maity, D., Kumar, S., AlHussein, R., Gremer, L., Howarth, M., Karpauskaite, L., Hoyer, W., Magzoub, M. & Hamilton, A.D. (2020) Sub-stoichiometric inhibition of IAPP aggregation: A peptidomimetic approach to anti-amyloid agents. RSC Chem. Biol., in press.
Selected as a Cover Article.
L. Palanikumar, Al-Hosani, S., Kalmouni, M., Saleh, H. & Magzoub, M.* (2020) Hexokinase II-derived cell-penetrating peptide mediates delivery of microRNA mimic for cancer-selective cytotoxicity. Biochemistry 59, 2259−2273.
Magzoub, M. (2020) Combating Proteins with Proteins: Engineering cell-penetrating peptide antagonists of amyloid-β aggregation and associated neurotoxicity. DNA and Cell Biology 39, 920–925.
L. Palanikumar, Al-Hosani, S., Kalmouni, M., Nguyen, V.P., Ali, L., Pasricha, R., Barrera, F.N. & Magzoub, M.* (2020) pH-responsive high stability polymeric nanoparticles for targeted delivery of anticancer therapeutics. Commun. Biol. 3, 95.
Selected as a Research Highlight and a Cover Article.
Highlighted in the editorial "Setting out on a fantastic voyage to advance nanomedicine".
Sharma, S.K.S., Al-Hosani, S., Kalmouni, M., Nair, A.R., Palanikumar, L., Pasricha, R., Sadler, K.C., Magzoub, M. & Jagannathan, R. (2020) Supercritical CO2 processing generates aqueous cisplatin with enhanced cancer specificity. ACS Omega 5, 4558−4567.
Henning-Knechtel, A., Kumar, S., Wallin, C., Król, S., Wärmländer, S., Jarvet, J., Esposito, G., Kirmizialtin, A., Gräslund, A., Hamilton, A.D. & Magzoub, M.* (2020) Designed cell-penetrating peptide inhibiters of amyloid-beta (Aβ) aggregation and cytotoxicity. Cell Rep. Phys. Sci. 1,100014.
Background: Small molecule inhibitors of amyloid-beta, designed and created by Khulood Alawadi, NYUAD.